Professors

Name:Ju-Sheng Lin

Chief Physician & Ph.D. supervisor;
National Second-Grade professor;
Serving Chairman of Hubei Association of the Study of Liver Disease;
Speically-Appointed professor of HUST;
Director of the Institute of Liver Disease of Tongji Hospital;
Leading expert of postdoctoral station of Tongji Hospital;
Standing Committee Member of Academic Board of Tongji Hospital;
Member of New and Advanced Techniques Steering Committee;
Editorial Board Member of Journal of Huazhong University of Science and Technology (Medical Sciences),Chinese Journal of Hepatology, Chinese Journal of Clinical Hepatology, etc;
Project Evaluation Expert of National Natural Science Foundation of China;
Council Member of Hubei Society of Biotechnology;
Former Committee Member of Chinese Society of Hepatology, Chinese Medical Association;
Former Deputy Director of Liver Cancer Study Group, Chinese Society of Hepatology, Chinese Medical Association;
Member of American Association for Cancer Research(AACR);
Member of Society of Chinese Bioscientists in America(SCBA);
Outstanding Middle-Aged & Young Expert of Hubei Awarded with Special Allowance from State Council.

Educational Background

Nov.2002-Feb.2003   Senior visiting scholar, Yale University
1999                           Senior visiting scholar, Tokyo Medical and Dental University and Juntendo University
1995-1997                  PostDoc. Yale University
1991                           Ph.D. of Internal Medicine, Tongji Medical University
1983                           M.D.,Tongji Medical University
1976                           B.S.,Fujian Medical University

Research

Professor Ju-Sheng Liu mainly engages in digestive system diseases, especially the molecular biology, genomics and epigenetics study of liver diseases, including the following: molecular mechanism and targeted therapy of primary hepatocellular carcinoma, host genetic factor of the clinical outcomes of hepatitis B virus infection, molecular biology and visualization study of hepatitis B virus; clinical diagnosis and therapy study of various virus hepatitis, alcoholic liver disease, fatty liver, drug-induced liver injury, hereditary and metabolic liver disease, autoimmune liver disease, liver fibrosis, cirrhosis, carcinoma and relevant complications.

Key Projects Involved

Professor Lin Ju-Sheng was the host of one key project and six surface projects of National Natural Science Foundation of China, one Foundation Project of Ministry of Health, one Doctor Station Foudation of Ministry of Education, one subproject of 973 Program and one subproject of 863 Program.
1. Title of project: Transferring receptor expression and receptor monoclonal antibody biological orientation in hepatocelluar carcinoma.
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation of china
Duration of the project: 1992-1994
Item number of the project: 39170828     
This project was admitted as international-advanced and was awarded with Third prize of Science and Technology Progress by National Education Committee.

2. Title of project: Structure-activity relationship and mechanism of new anti-EB virus nucleoside analogue.
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation of China
Duration of the project: 1998-2000
Item number of the project: 39770867

3. Title of project: Screening model and new compound of anti-hepatitis B virus drug.
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation of China
Duration of the project: 2000-2002
Item number of the project: 39970858
  
4. Title of project: The role of ribozyme in the genetic therapy for hepatitis B virus.
Leader of project: Professor Lin Ju-Sheng
Support of project: Ministry of Health Foundation Project
Duration of the project: 1998-1999
Item number of the project: 98-1-140
 
5. Title of project: Trf mediates the restoration of hepatic tumor suppressor gene by trans-splicing ribozyme. 
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation of China
Duration of the project: 2002.1-2004.12
Item number of the project: 30171061
 
6.  Title of project: Mechanisms of new anti-hepatitis B virus drug.
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation Key Project of China
Duration of the project: 2004.1-2007.12
Item number of the project: 30330680

7. Title of project: Genetic imprinted gene PEG10, a potential new molecular target of gene therapy for hepatocelluar carcinoma.
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation Surface Project of China
Duration of the project: 2005.1-2007.12
Item number of the project: 30471983

8. Title of project: Host molecular hereditary features of chronic severe hepatitis B.
Leader of project: Professor Lin Ju-Sheng
Support of project: subproject of 973 program
Duration of the project: 2007.7-2012.12
Item number of the project: 2007CB512903
 
9. Title of project: A new strategy of intervention for HBV-induced hepatocelluar carcinoma: modulation of DSB restoration started by two gating proteins inhibits the integration of HBV.
Leader of project: Professor Lin Ju-Sheng
Support of project: National Natural Science Foundation of China
Duration of the project: 2009.1-2011.12
Item number of the project: 30872237

Honors & Awards

1. Third prize of Science and Technology Progress awarded by National Education Committee (1994)
2. National Second-grade Professor (2008)
3. Tongji Scientist (2011)

Publication

Professor Ju-Sheng Liu has published over 200 papers home and aborad, in which over 20 were included by SCI. He is the Chief editor of Modern Protocols in Cell & Molecular Biology, Deputy editor of Hepatology and Digestive System Disease (National High School Medical Postgraduate designatied Textbook ). He is also involved in compiling of Clinical Digestive System Disease, Portal Hypertension and Gene Therapy for Cancer, etc.