Professors

Name:An-Min Chen

President and Secretary of the Communist Party of China’s Committee of Tongji Hospital, Professor, Department of Orthopaedic Surgery, Tongji Hospital, Huazhong University of Science and Technology;
Director, Basic Research Group of Chinese Orthopaedic Association;
Standing Committee Member of Chinese Orthopaedic Association;
Director-General of Chinese & Germany Medical Association;
Chairman, Orthopaedic Trauma Association of Hubei Province;
Vice Chairman, Orthopaedic Association of Hubei Province.

Educational Background

1993-Now   Professor, Department of Orthopaedic Surgery, School of Medicine, Huazhong University of Science and Technology
1993-1995  Postdoctoral Fellowship, University of Innsbruck, Innsbruck, Austria
1985-1992  Attending Doctor, Tongji Hospital, Tongji Medical University
1978-1981  Resident, the 2nd Hospital of Hubei Medical University
1990          Ph.D, Tongji Medical University
1985          M.S., Tongji Medical University
1979          B.S., Tongji Medical University

Research

Prof. Chen has been devoting his efforts on Orthopaedic Surgery for almost 30 years. Specifically, Prof. Chen and his team are working on the basic research about tissue engineering methods to repair of cartilage damage, bone fracture or bone defect by the pre-cartilage stem cells and stem cells from other source. His clinical contributions also include the development to the hip and knee arthroplasty, surgical treatment to sports injuries, bone injuries and other spinal diseases. While serving as a professor at the School of Medicine and Health Management and President of Tongji hospital, he creates innovations about the hospital management and performance management.

Key Projects Involved

Prof. Chen has received funding from a variety of sources, including the Ministry of Health, Ministry of Education, Ministry of Science and Technology, National Natural Science Foundation of China.

Honors & Awards

1. National Labor Model by the State Council of China, 2010
2. Provincial Award for Science and Technology Progress, by Hubei Provincial Science & Technology Department, 2009
3. National May 1 Labor Medal, by All China Federation of Trade Unions, 2006
4. Outstanding Contribution to Hospital Management Award, by Chinese Hospital Association, 2003
5. 100 National Excellent Presidents of Hospital, by Chinese Hospital Association, 2002
6. National Excellent Education Workers, by the Ministry of Education of China, 2001
7. Doctor with Outstanding Contributions, by Academic Degree Committee of the State Council of China, 1992Young Expert with Outstanding Contributions, by Ministry of Health of China, 1992State Council Expert for Special Allowance, by State Council of China, 1992

Publication

1. Qi J, Chen A, Guo F, et al. Proliferation and chondrogenic differentiation of CD105-positive enriched rat synovium-derived mesenchymal stem cells in three-dimensional porous scaffolds. Biomed Mater, 2011, 6(1):015006
2. Zhang F, Chen A, Guo F, et al. SiRNA-mediated silencing of beta-catenin suppresses invasion and chemosensitivity to doxorubicin in MG-63 osteosarcoma cells. Asian Pac J Cancer Prev, 2011, 12(1):239-45.
3. Liu H, Chen A, Guo F, et al. A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells. Cancer Lett, 2010, 295(1):27-37
4. Xu K, Guo F, Zhang S, Liu C, Wang F, Zhou Z, Chen A. Blocking Ihh Signaling Pathway Inhibits the Proliferation and Promotes the Apoptosis of PSCs. J Huazhong Univ Sci Technolog Med Sci. 2009 Feb;29(1):39-44.
5. Hu W, Guo F, Li F, Huang H, Zhang W, Chen A. Construction of Sox9 Gene Eukaryotic Expression Vector and Its Inductive Effects on Directed Differentiation of Bone Marrow Stromal Cells into Precartilaginous Stem Cells in Rats. J Huazhong Univ Sci Technolog Med Sci. 2009 Jun;29(3):291-5.
6. Wang J, Fang H, Xia R, Chen A, Cheng H. Immortalization of human precartilaginous stem cells by transfecting SV40Tag. J Huazhong Univ Sci Technolog Med Sci. 2009 Apr;29(2):231-4. 7. Zhang S, Chen A, Hu W, Li M, Liao H, Zhu W, Song D, Guo F. Immunological purification of rat precartilaginous stem cells and construction of the immortalized cell strain. Arch Orthop Trauma Surg. 2008 Nov;128(11):1339-44.
8. Pan F, Chen A, Guo F, Zhu C, Tao F. Effect of FK506 on expression of hepatocyte growth factor in murine spinal cord following peripheral nerve injury. J Huazhong Univ Sci Technolog Med Sci. 2008 Apr;28(2):159-62.
9. Peng S, Xia R, Fang H, Li F, Chen A, Zhang G, Qin L. Effect of epimedium-derived phytoestrogen on bone turnover and bone microarchitecture in OVX-induced osteoporotic rats. J Huazhong Univ Sci Technolog Med Sci. 2008 Apr;28(2):167-70.
10. Huang H, Chen A, Guo F, et al. CK1 β-catenin-mediated transcription, epidermal stem cell expansion, and differentiation. Am J Dermatopath, 2007, 104(32): 13040-13045.
11. Yang C, Zhu B, Chen A. Imaging diagnosis of monostotic fibrous dysplasia in thoracic and lumbar spine vertebrae. J Huazhong Univ Sci Technolog Med Sci. 2007 Dec;27(6):684-6.
12. Guo F, Zhang Y, Chen A, et al. Effect of stathmin decoyoligo-deoxynucleotides on the proliferation and differentiation of pre-cartilaginous stem cell. J Huazhong Univ Sci Technolog Med Sci, 2007, 27(5):557-60
13. Fang H, Yang X, Chen A, Luo Y. Effect of rhBMP-2 and osteogenic revulsants on proliferation and differentiation of bone marrow stromal cells in rats. J Huazhong Univ Sci Technolog Med Sci. 2007 Oct;27(5):561-3.
14. Shi XB, Chen A, Cai XH, Guo F, Liao G, Ma D. Establishment and characterization of cell sublines with high and low metastatic potential derived from human osteosarcoma. Chin Med J (Engl). 2005 Apr 20;118(8):687-90.